abstract：AIM:To explore the relationship of clinicopathological features and the proteins of C-met expression in the prognosis of cholangiocarcinoma. METHODS:Clinical data and the completed follow-up information of patients with cholangiocarcinoma who underwent cholangiocarcinoma operation from January 2004 to December 2010 we...

journal_title：Technology in cancer research & treatment

authors： Mao ZY,Zhu GQ,Ren L,Guo XC,Su D,Bai L

更新日期：2016-04-01 00:00:00

abstract：PURPOSE:To evaluate 2 simultaneous integrated boost treatment planning techniques using helical tomotherapy for breast conserving therapy with regard to acute skin toxicity and dosimetry. METHODS:Thirty-two patients were studied. The original approach was for 16 patients and incorporated a directional block of the ips...

journal_title：Technology in cancer research & treatment

authors： Wojcieszynski AP,Olson AK,Rong Y,Kimple RJ,Yadav P

更新日期：2016-04-01 00:00:00

abstract：:Fascin is overexpressed in various tumor tissues and is closely related to tumor metastasis and invasion. However, the role of fascin in cholangiocarcinoma RBE cells has not been clearly reported. This study aimed to establish a cholangiocarcinoma cell line with stable and high expression of fascin to observe the effe...

journal_title：Technology in cancer research & treatment

authors： Zhao H,Yang F,Zhao W,Zhang C,Liu J

更新日期：2016-04-01 00:00:00

abstract：:Growing evidence suggests that aberration of the DNA repair pathway significantly contributes to tumorigenesis. Single-nucleotide polymorphisms in DNA repair-related genes such as WRN have been implicated in cancer risk. However, the results of published studies remain inconclusive. Therefore, we performed a meta-anal...

journal_title：Technology in cancer research & treatment

authors： Wang B,Li G,Sun F,Dong N,Sun Z,Jiang D

更新日期：2016-02-01 00:00:00

abstract：:This study quantifies the setup uncertainties to optimize the planning target volume (PTV) margin based on daily image guidance, its dosimetric impact, and radiobiological implication for intensity-modulated radiation therapy (IMRT) in head and neck cancer. Ten patients were retrospectively chosen who had been treated...

journal_title：Technology in cancer research & treatment

authors： Srivastava SP,Cheng CW,Das IJ

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:The aim of this study was to evaluate the efficacy and toxicity of robotic CyberKnife (Accuray Incorporated, Sunnyvale, California)-based stereotactic body radiation therapy (SBRT) in patients with recurrent or metastatic abdominopelvic tumors. METHODS AND MATERIALS:A total of 69 patients treated between Ma...

journal_title：Technology in cancer research & treatment

authors： Sezen D,Gurkaynak M,Gultekin M,Cengiz M,Yildiz F,Zorlu F,Akyol F,Yazici G,Hurmuz P,Ozyigit G

更新日期：2016-02-01 00:00:00

abstract：:Chemo-radiotherapy is standard treatment of stage IIIA-N2 bulky or IIIB non-small cell lung cancer (NSCLC). Surgical resection of residual disease in downstaged patients may improve overall survival. In this setting, restaging disease is still a challenge. 18F-FDG PET/CT represents the gold standard although accuracy ...

journal_title：Technology in cancer research & treatment

authors： Genestreti G,Burgio MA,Matteucci F,Piciucchi S,Scarpi E,Monti M,Bucchi L,Parisi E,Crociani L,Gurioli C,Poletti V,Gavelli G

更新日期：2015-12-01 00:00:00

abstract：:Recombinant Newcastle Disease Virus (rNDV) has shown oncolytic therapeutic effect in preclinical studies. Previous data indicate that rNDV carrying IL2 has shown promise in cancer therapy. Due to the significant side effects of IL2, IL15 has been introduced into cancer therapy. A number of studies have suggested that ...

journal_title：Technology in cancer research & treatment

authors： Niu Z,Bai F,Sun T,Tian H,Yu D,Yin J,Li S,Li T,Cao H,Yu Q,Wu Y,Ren G,Li D

更新日期：2015-10-01 00:00:00

abstract：:The inhibitor of growth (ING) family proteins have been defined as candidate tumor suppressors. ING4 as a novel member of ING family has potential tumor-suppressive effects via multiple pathways. However, the therapeutic effect of adenovirus-mediated ING4 (Ad-ING4) gene transfer in human osteosarcoma is still unknown....

journal_title：Technology in cancer research & treatment

authors： Xu M,Xie Y,Sheng W,Miao J,Yang J

更新日期：2015-10-01 00:00:00

abstract：:Volumetric modulated arc therapy (VMAT) has been adopted by many clinics for its higher delivery efficiency compared to conventional intensity modulated radiotherapy techniques. Currently, the quality assurance (QA) has remained a challenge in that no identical tests are available for accelerators from different vendo...

journal_title：Technology in cancer research & treatment

authors： Wang J,Hu W,Peng J,Lu S,Zhao J,Xiao Y,Zhang Z

更新日期：2015-08-01 00:00:00

abstract：:eLiposomes encapsulate a perfluorocarbon nanoemulsion droplet inside a liposome. Ultrasound is then used as a trigger mechanism to vaporize the perfluorocarbon, break the liposome, and release the desired drug to the tumor tissue. The purpose of this research is to show that eLiposomes synthesized using perfluoropenta...

journal_title：Technology in cancer research & treatment

authors： Husseini GA,Pitt WG,Javadi M

更新日期：2015-08-01 00:00:00

abstract：:The objective of this study is to compare the new and conventional tomotherapy treatment techniques and to evaluate dosimetric differences between them. A dosimetric analysis was performed by comparing planning target volume (PTV) median dose, 95% of PTV dose coverage, Paddick conformity index (CI), homogeneity index ...

journal_title：Technology in cancer research & treatment

authors： Zhang X,Penagaricano J,Han EY,Morrill S,Hardee M,Liang X,Gupta SK,Corry PM,Ratanatharathom V

更新日期：2015-08-01 00:00:00

abstract：:This article proposes quantitative analysis tools and digital phantoms to quantify intrinsic errors of deformable image registration (DIR) systems and establish quality assurance (QA) procedures for clinical use of DIR systems utilizing local and global error analysis methods with clinically realistic digital image ph...

journal_title：Technology in cancer research & treatment

authors： Kim H,Park SB,Monroe JI,Traughber BJ,Zheng Y,Lo SS,Yao M,Mansur D,Ellis R,Machtay M,Sohn JW

更新日期：2015-08-01 00:00:00

abstract：:This study aimed to analysis outcome and prognosis of interstitial 125I seed implantation in patients with cervical lymph node recurrence after multimodal treatment of thoracic esophageal squamous cell carcinoma (ESCC). We conducted a retrospective review of 19 patients with 32 cervical lymph nodes recurrences after m...

journal_title：Technology in cancer research & treatment

authors： Lin L,Wang J,Jiang Y,Meng N,Tian S,Yang R,Ran W,Liu C

更新日期：2015-04-01 00:00:00

abstract：:Hydroxycamptothecin-encapsulated chitosan (HC) nanospheres were prepared by Shirasu porous glass (SPG) membrane emulsification technique. The properties and morphology of HC nanospheres were characterized. The diameter of the nanospheres could be controlled within a narrow distribution according to the pore-size of SP...

journal_title：Technology in cancer research & treatment

authors： Han J,Hou ZQ,Wang YG,Guo X

更新日期：2015-02-01 00:00:00

abstract：:Irreversible electroporation (IRE) has been shown to be an effective method of killing cells locally. In contrast to radiofrequency ablation, the mechanism by which cells are thought to die via IRE is the creation of pores in cell membranes, without substantial increase in tissue temperature. To determine the degree t...

journal_title：Technology in cancer research & treatment

authors： Long G,Bakos G,Shires PK,Gritter L,Crissman JW,Harris JL,Clymer JW

更新日期：2014-12-01 00:00:00

abstract：:The integrated use of optical technologies for patient monitoring is addressed in the framework of time-resolved treatment delivery for scanned ion beam therapy. A software application has been designed to provide the therapy control system (TCS) with a continuous geometrical feedback by processing the external surrog...

journal_title：Technology in cancer research & treatment

authors： Fattori G,Saito N,Seregni M,Kaderka R,Pella A,Constantinescu A,Riboldi M,Steidl P,Cerveri P,Bert C,Durante M,Baroni G

更新日期：2014-12-01 00:00:00

abstract：:The accurate characterization and description of the vascular network of a cancer lesion is of paramount importance in clinical practice and cancer research in order to improve diagnostic accuracy or to assess the effectiveness of a treatment. The aim of this study was to show the effectiveness of liposomes as an ultr...

journal_title：Technology in cancer research & treatment

authors： Molinari F,Meiburger KM,Giustetto P,Rizzitelli S,Boffa C,Castano M,Terreno E

更新日期：2014-12-01 00:00:00

abstract：:The aim of this retrospective study is to evaluate our therapeutic results in patients with paranasal sinus (PNS) or nasal cavity (NC) malignancies treated with robotic stereotactic radiosurgery (SRS). Between August 2007 and October 2008, 27 patients with PNS or NC tumors were treated in our department using SRS. Med...

journal_title：Technology in cancer research & treatment

authors： Ozyigit G,Cengiz M,Hurmuz P,Yazici G,Gultekin M,Akyol F,Yildiz F,Gurkaynak M,Zorlu F

更新日期：2014-10-01 00:00:00

abstract：:The PIN diode developed by Bhabha Atomic Research Centre (BARC) was modified for its use as a dosimeter in radiation therapy. For this purpose the diode was mounted on a printed circuit board (PCB) and provided with necessary connections so that its response against irradiation can be recorded by a standard radiothera...

journal_title：Technology in cancer research & treatment

authors： Kumar R,Sharma SD,Philomina A,Topkar A

更新日期：2014-08-01 00:00:00

abstract：UNLABELLED:The purpose of this study was to compare the prognostic value of the percentage of positive biopsy cores (PPBC), the percentage of cancer volume (PCV), and the maximum involvement of biopsy cores (MIBC) as a prognostic factor in low- and intermediate-risk patients with clinically localized prostate cancer wh...

journal_title：Technology in cancer research & treatment

authors： Slater JM,Bush DA,Grove R,Slater JD

更新日期：2014-06-01 00:00:00

abstract：:Colorectal cancer is one of the most common cancers in the world. Protein phosphatase magnesium-dependent 1 d (PPM1D) is aberrantly upregulated in many human carcinoma cells, and recent research has suggested that it could be a potential therapeutic target of cancer. However, the function of PPM1D in colorectal carcin...

journal_title：Technology in cancer research & treatment

authors： Yin H,Yan Z,Liang Y,Liu B,Su Q

更新日期：2013-12-01 00:00:00

abstract：:Glucose transporter 1 (GLUT1) facilitates the cellular uptake of glucose and is overexpressed in most cancers. The altered expression of GLUT1 may influence the sensitivity of tumor cells to chemotherapy. This study investigated whether the knockdown of GLUT1 expression to sensitize head and neck cancer cells to the c...

journal_title：Technology in cancer research & treatment

authors： Wang YD,Li SJ,Liao JX

更新日期：2013-12-01 00:00:00

abstract：:The increasing evidence supported the role of Enhancer of Zeste Homolog 2 (EZH2) in the cancer development and progression. However, its precise role in the tumorigenesis of Nasopharyngeal Carcinoma (NPC) remains to be elucidated. EZH2 was depleted by retroviral infection in the NPC cells (HK-1, CNE-2, CNE-1 and C666-...

journal_title：Technology in cancer research & treatment

authors： Zhong J,Min L,Huang H,Li L,Li D,Li J,Ma Z,Dai L

更新日期：2013-06-01 00:00:00

abstract：:The aim of this study is to evaluate the volume differences between contrast-enhanced CT-based left ventricle (LV) and PET-CT-based LV and assess the impact of dose on the substructure volume differences in patients with left breast cancer treated with adjuvant radiotherapy. From October 2008 to February 2009, 14 pati...

journal_title：Technology in cancer research & treatment

authors： Yu XL,Zhang Q,Chen JY,Zhang Z,Wang JZ,Hu WG,Pan ZQ,Hu SL,Zhang YJ,Feng Y,Shao ZM,Orecchia R,Guo XM

更新日期：2013-04-01 00:00:00

abstract：:Dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) is able to detect breast cancer with high sensitivity. Furthermore, this method provides functional information on tissue composition and vascularization. This study aims to identify the potential of DCE-MRI to predict distant metastasis in breast cancer p...

journal_title：Technology in cancer research & treatment

authors： Baltzer PA,Zoubi R,Burmeister HP,Gajda M,Camara O,Kaiser WA,Dietzel M

更新日期：2012-12-01 00:00:00

abstract：:Despite remarkable progress in diagnosis and treatment, malignant glioma, a highly lethal cancer of the central nervous system, remains incurable. Although glioma stem-like cells (GSCs) represent a relatively small fraction of the cells in malignant glioma, they can proliferate and self renew extensively, being crucia...

journal_title：Technology in cancer research & treatment

authors： Xu ZY,Li XQ,Chen S,Cheng Y,Deng JM,Wang ZG

更新日期：2012-12-01 00:00:00

abstract：:Blood flow is a key parameter in studying cancer angiogenesis and hypermetabolism. Current photoacoustic blood flow estimation methods focus on either the axial or transverse component of the flow vector. However, the Doppler angle (beam-to-flow angle) is needed to calculate the total flow speed, and it cannot always ...

journal_title：Technology in cancer research & treatment

authors： Yao J,Maslov KI,Wang LV

更新日期：2012-08-01 00:00:00

abstract：:The coupling mechanism between neuronal firing and cerebrovascular dilatation can be significantly compromised in cerebral diseases, making it difficult to identify eloquent cortical areas near or within resectable lesions by using Blood Oxygen Level Dependent (BOLD) fMRI. Several metabolic and vascular factors have ...

journal_title：Technology in cancer research & treatment

authors： Pillai JJ,Zacà D

更新日期：2012-08-01 00:00:00

abstract：:Malignant pleural mesothelioma (MPM) is a rare and aggressive tumor with generally disappointing results in terms of survival, however, there are occasional long-term survivors probably due to the biologic characteristics of the disease. Standard uptake value (SUV) of [(18)F] Fluorodeoxyglucose (FDG) evaluated by phot...

journal_title：Technology in cancer research & treatment

authors： Genestreti G,Moretti A,Piciucchi S,Tiseo M,Bersanelli M,Scarlattei M,Scarpi E,Dubini A,Matteucci F,Sanna S

更新日期：2012-04-01 00:00:00

abstract：:Radiotherapy is frequently indicated to treat cerebral gliomas. Accurate response evaluation after radiotherapy is essential to determine the efficacy of treatment. We retrospectively analyzed the volumetric tumor response after simultaneous integrated boost-intensity modulated radiotherapy (SIB-IMRT) in patients with...

journal_title：Technology in cancer research & treatment

authors： Cho KH,Choi JH,Kim JY,Lee SH,Yoo H,Shin KH,Kim TH,Moon SH,Lee SH,Park HC

更新日期：2012-02-01 00:00:00

abstract：:The aim of this paper is to study the feasibility for determining the individual internal target volume (ITV) for hepatocellular carcinoma (HCC) using 3DCT associated with active breathing coordinator (ABC), comparing the ITVs defined by 3DCT associated with ABC and 4DCT. Thirteen patients with HCC after transarterial...

journal_title：Technology in cancer research & treatment

authors： Gong G,Yin Y,Xing L,Guo Y,Chen J,Liu T,Lu J,Ma C,Sun T,Bai T,Zhang G,Deng W

更新日期：2011-12-01 00:00:00

abstract：:A fiber confocal back scattering micro-spectrometer (FCBS) was established, which combined fiber confocal microscopy with light scattering spectroscopy (LSS) for early diagnosis of the cancer cell at cellular level. An adherent monolayer human normal gastric epithelium line GES-1 and a carcinoma cell line NCI-N87 as w...

journal_title：Technology in cancer research & treatment

authors： Wang C,Li Y,Liu G,Ma J,Li Z,Wei X

更新日期：2011-10-01 00:00:00

abstract：:Planning robotic radiosurgery treatments for multiple (n > 3) metastatic brain lesions is challenging due to the need of satisfying a large number of dose-volume constraints and the requirement of prescribing different dose levels to individual targets. In this study, we developed a sequential two-step optimization te...

journal_title：Technology in cancer research & treatment

authors： Ma L,Sahgal A,Hwang A,Hu W,Descovich M,Chuang C,Barani I,Sneed PK,McDermott M,Larson DA

更新日期：2011-08-01 00:00:00

abstract：:This study was designed to estimate the risk of radiation-associated tumors and clinical toxicity in the brain following fractionated radiation treatment of pituitary adenoma. A standard case of a patient with a pituitary adenoma was planned using 8 different dosimetric techniques. Total dose was 50.4 Gy (GyE) at dail...

journal_title：Technology in cancer research & treatment

authors： Winkfield KM,Niemierko A,Bussiere MR,Crowley EM,Napolitano BN,Beaudette KP,Loeffler JS,Shih HA

更新日期：2011-06-01 00:00:00

abstract：:Optical methods such as reflectance and fluorescence spectroscopy are being investigated for their potential to aid cancer detection in a quantitative, minimally invasive manner. Mathematical models of reflectance and fluorescence provide an important link between measured optical data and biomedically-relevant tissue...

journal_title：Technology in cancer research & treatment

authors： Wilson RH,Mycek MA

更新日期：2011-04-01 00:00:00

abstract：:Non-thermal irreversible electroporation (N-TIRE) has shown promise as an ablative therapy for a variety of soft-tissue neoplasms. Here we describe the therapeutic planning aspects and first clinical application of N-TIRE for the treatment of an inoperable, spontaneous malignant intracranial glioma in a canine patient...

journal_title：Technology in cancer research & treatment

authors： Garcia PA,Pancotto T,Rossmeisl JH Jr,Henao-Guerrero N,Gustafson NR,Daniel GB,Robertson JL,Ellis TL,Davalos RV

更新日期：2011-02-01 00:00:00

abstract：:We describe the first histopathologic analysis of prostatic tissue following hypofractionated robotic radiation therapy. A 66 year-old man presented with stage II, low risk adenocarcinoma of the prostate and underwent elective conformal hypofractionated radiation therapy. His pretreatment evaluation revealed T1c adeno...

journal_title：Technology in cancer research & treatment

authors： Suy S,Oermann E,Hanscom H,Lei S,Vahdat S,Yu X,Park HU,Chen V,Collins BT,McGeagh K,Dawson N,Jha R,Azumi N,Dritschilo A,Lynch J,Collins SP

更新日期：2010-12-01 00:00:00

abstract：:Endoscopic endonasal surgery (EES) has been shown to be a feasible approach to cranial base tumors while reducing post-operative morbidity. Using the endoscopic endonasal approach alone or in combination with open approaches may provide advantages over conventional approaches. However, the balance between maximal rese...

journal_title：Technology in cancer research & treatment

authors： Paravati AJ,Heron DE,Gardner PA,Snyderman C,Ozhasoglu C,Quinn A,Burton SA,Seelman K,Mintz AH

更新日期：2010-10-01 00:00:00

abstract：:Intraoperative MRI (iMRI) is used in glioma surgery mainly to determine the extent of resection, allowing surgeons to immediately continue resection in case of residual tumor tissue. The aim of this study is to report on the influence of the use of iMRI on the extent of resection and survival of patients with glioblas...

journal_title：Technology in cancer research & treatment

authors： Senft C,Franz K,Blasel S,Oszvald A,Rathert J,Seifert V,Gasser T

更新日期：2010-08-01 00:00:00